Anabel2054 331332 Min Upd Online

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Uniparental Disomy (UPD) occurs when an individual receives two copies of a chromosome, or part of a chromosome, from one parent and no copy from the other. Detecting UPD is critical in clinical genomics for diagnosing imprinting disorders and recessive diseases. This paper discusses the methodology for detecting the "Minimum UPD" region—defined as the smallest contiguous segment of genetic markers that satisfies the criteria for UPD—using computational approaches. We analyze a specific dataset instance referenced as anabel2054 331332 to demonstrate the efficiency of sliding window algorithms and genotype consistency checks in minimizing the identified UPD interval.

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